Bilateral Hypoglossal Nerve Stimulation (Nyxoah System)
The definitive alternative to CPAP: wireless micro-stimulation technology for the treatment of Obstructive Sleep Apnea (OSA).
The End of Machine Dependence
Many patients with moderate to severe Obstructive Sleep Apnea (OSA) cannot adapt to the positive pressure mask (CPAP). Poor adherence not only affects rest but also increases cardiovascular risk.
The Nyxoah (Genio™) system represents a generational leap: it is the first bilateral hypoglossal nerve stimulation system that keeps the airways open through gentle activation of the tongue muscles, allowing natural breathing without obstructions throughout the night.
How Does Nyxoah Technology Work?
Unlike other implants, Nyxoah uses a bilateral stimulation approach.
The Implant
A tiny micro-stimulator is placed on the hypoglossal nerve through a minimally invasive surgery under the chin.
No Internal Batteries
The device has no internal battery, which avoids future surgeries for replacements.
Patch Activation
Each night, the patient places a small adhesive patch under the chin. This patch transmits energy and data to the implant wirelessly, activating therapy only when needed.
Clinical Evidence and Benefits
Based on the latest clinical trials (BLAST-OSA and Elios studies), patients report:
- AHI Reduction: Significant decrease in respiratory events per hour.
- Quality of Life Improvement: Drastic reduction of daytime sleepiness and mood improvement.
- Outpatient Surgery: The procedure usually takes less than one hour and the patient goes home the same day or within 24h.
Are You a Candidate for the Nyxoah Implant?
This procedure is indicated for patients who meet the following medical criteria:
- Diagnosis of moderate to severe OSA (AHI between 15 and 65).
- CPAP failure or intolerance (inability to use for more than 4 hours per night).
- Airway Evaluation: Absence of complete concentric collapse in the oropharynx (verified by sleep endoscopy or DISE).
- BMI < 35: Treatment is more effective in patients without morbid obesity.
Nyxoah vs. Other Treatments
| Feature | CPAP | Airway Surgery | Nyxoah |
|---|---|---|---|
| Comfort | Low (mask/noise) | Variable | High (invisible) |
| Invasiveness | None | High | Minimal |
| Long-term Efficacy | Use-dependent | Variable | Consistent |
| Batteries/Cables | Power cable | N/A | No internal cables |
| Adherence | Low (40-60%) | N/A | High (>80%) |
CE Marking & Clinical Validation
The Nyxoah Genio® system has CE marking for clinical use in Europe and is backed by multicenter clinical trials (BLAST-OSA, Elios).
Frequently Asked Questions
Have you been diagnosed with Apnea?
Use our Positional Therapy App to monitor your posture before the implant.
Explore Positional TherapyWe analyze your case through Sleep Endoscopy (DISE) to determine if Nyxoah is the definitive solution for your rest.
Request Candidacy Evaluation